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LSD Documents
Documents about LSD, Lysergic acid diethylamide, Acid, LSD-25
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  "LSD, Dogs and Me," by Robert Anton Wilson Left click: open entry/Right click: save entry

  --written for a Swiss magazine, on the 60th anniversary of Dr Hoffman's discovery of LSD.


In memory of Robert Anton Wilson.
 
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Submitted by enquirewithin Find all entries from this user
21-04-2007
46.09 Kbytes Hits 237
Keywords: lsd
  'Candyflipping': synergistic discriminative effect of LSD and MDMA (1998) Left click: open entry/Right click: save entry 5 *
Eur J Pharmacol. 1998 Jan 12;341(2-3):131-4

Schechter MD.

The co-administration of D-lysergic acid diethylamide (LSD; 'Acid') and 3,4-methylenedioxymethamphetamine (MDMA; 'Ecstasy'; 'XTC'), has reached a prevalence that has allowed for the street terminology 'candyflipping' to describe the...
 
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Submitted by Alfa Find all entries from this user
01-06-2006
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Keywords: mdma lsd candy-flip
'Intelligence Agents,' by Timothy Leary
One of Leary's later books.  
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Submitted by enquirewithin Find all entries from this user
22-02-2006
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  'The Varieties of Psychedelic Experience,' by Masters and Houston Left click: open entry/Right click: save entry
Another classic text about hallucinogens from 1966.  
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Submitted by enquirewithin Find all entries from this user
23-02-2006
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  5-hydroxytryptamine (serotonin) 2a receptors in rat anterior cingulate cortex mediate the discriminative stimulus properties of d-lysergic acid diethylamide (2007) Left click: open entry/Right click: save entry
J Pharmacol Exp Ther. 2007 Feb;320(2):662-9

Gresch PJ, Barrett RJ, Sanders-Bush E, Smith RL.

d-Lysergic acid diethylamide (LSD), an indoleamine hallucinogen, produces profound alterations in mood, thought, and perception in humans. The brain site(s) that mediates the effects of LSD is...
 
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Submitted by Heretic.Ape. Find all entries from this user
24-05-2007
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  A chronic impairment or colour vision in users of LSD Left click: open entry/Right click: save entry
Abraham HD.
“A chronic impairment of colour vision in users of LSD”.
Br J Psychiatry. 1982;140:518-20.
 
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Submitted by trptamene Find all entries from this user
08-09-2007
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Keywords: vision lsd
  A New Manual for Guides Left click: open entry/Right click: save entry
On November 3, National Geographic aired the first of several broadcasts of EXPLORER: Inside LSD. The producers did a good job of showing scientific research being done with LSD in different settings (past and current). The show included several segments about personal use. These ranged from...  
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Submitted by Anonymous Find all entries from this user
14-11-2009
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  A Single Dose of Lysergic Acid Diethylamide Influences Gene Expression Patterns within the Mammalian Brain (2002) Left click: open entry/Right click: save entry
Neuropsychopharmacology. 2002 May;26(5):634-42.

Nichols CD, Sanders-Bush E

Hallucinogenic drugs such as lysergic acid diethylamide (LSD) have profound effects on humans including hallucinations and detachment from reality. These remarkable behavioral effects have many similarities to the...
 
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Submitted by Alfa Find all entries from this user
01-06-2006
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  Acute adverse reactions to LSD in clinical and experimental use in the United Kingdom. Left click: open entry/Right click: save entry
Br J Psychiatry. 1971 Feb;118(543):229-30.
Malleson N.
 
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Submitted by ThirdEyeFloond Find all entries from this user
08-08-2008
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  Alterations in responses to LSD in humans associated with chronic administration of tricyclic antidepressants, monoamine oxidase inhibitors or lithium (1996) Left click: open entry/Right click: save entry
Behav Brain Res. 1996;73(1-2):229-33.

Bonson KR, Murphy DL.

This study sought to investigate possible interactions between antidepressant agents and lysergic acid diethylamide (LSD) in humans through the use of retrospective questionnaires. Ten subjects were identified who used LSD during...
 
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Submitted by Alfa Find all entries from this user
01-06-2006
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  Behavioural Tolerance to LSD is Associated with Reduced Serotonin-2A Receptor Signalling in Rat Cortex (2005) Left click: open entry/Right click: save entry
Neuropsychopharmacology. 2005 Sep;30(9):1693-702

Gresch PJ, Smith RL, Barrett RJ, Sanders-Bush E.

Tolerance is defined as a decrease in responsiveness to a drug after repeated administration. Tolerance to the behavioral effects of hallucinogens occurs in humans and animals. In this study,...
 
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Submitted by Jatelka Find all entries from this user
17-01-2007
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Keywords: tolerance serotonin lsd 5ht-2a
  Can LSD Enlarge the Mind? (Psychedelic Review, 1963) Left click: open entry/Right click: save entry
An early article on LSD titled, "Can This Drug Enlarge Man's Mind?" From the first volume of Psychedelic Review (Vol. I, No. 1, June 1963).

Author: Gerald Heard

Discussion Thread
 
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Submitted by Expat98 Find all entries from this user
31-05-2008
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  Chronic Administration of Serotonergic Antidepressants Attenuates the Subjective Effects of LSD in Humans (1996) Left click: open entry/Right click: save entry
Neuropsychopharmacology. 1996 Jun;14(6):425-36

Bonson KR, Buckholtz JW, Murphy DL.

This study investigates the possible interactions of antidepressant agents and hallucinogens in humans through structured interviews using a standardized questionnaire. Volunteer subjects recruited through...
 
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Submitted by Jatelka Find all entries from this user
23-11-2006
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Keywords: tolerance lsd ssri
  Clarifying the Confusion Regarding LSD-25 Left click: open entry/Right click: save entry
Savage, C., and M. J. Stolaroff. 1965. Clarifying the Confusion Regarding LSD-25. The Journal of Nervous and Mental Disease 140:218-221.  
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Submitted by turkeyphant Find all entries from this user
05-03-2007
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  Clonazepam treatment of lysergic acid diethylamide-induced hallucinogen persisting perception disorder with anxiety features Left click: open entry/Right click: save entry
Lerner, Arturo G. Rudinski, Dmitri.
Int Clin Psychopharmacol. Volume: 18, Issue: 2, Date: 2003 Mar , Pages: 101-5
 
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Submitted by ThirdEyeFloond Find all entries from this user
14-01-2008
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  Coma, Hyperthermia and Bleeding Associated with Massive LSD Overdose a Report of Eight Cases (1974) Left click: open entry/Right click: save entry
West J Med. 1974 Mar;120(3):183-8.

Klock JC, Boerner U, Becker CE.

Eight patients were seen within 15 minutes of intranasal self-administration of large amounts of pure D-lysergic acid diethylamide (LSD) tartrate powder. Emesis and collapse occurred along with signs of sympathetic...
 
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Submitted by trptamene Find all entries from this user
03-11-2007
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  Comparison of psilocin with psilocybin, mescaline and LSD-25 Left click: open entry/Right click: save entry
Received: 6 February 1962

Summary
1. Reactions induced by LSD, mescaline, psilocin, and psilocybin are qualitatively similar.
2. The time course of the psilocin and psilocybin reactions are shorter than those of LSD or mescaline reactions. li
4. Psilocin is approximately 1.4 times...
 
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11-12-2009
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  Complex Discriminative Stimulus Properties of LSD in C57BL/6J Mice (2005) Left click: open entry/Right click: save entry
Psychopharmacology (Berl). 2005 Jun;179(4):854-62.

Benneyworth MA, Smith RL, Barrett RJ, Sanders-Bush E.

RATIONALE: The drug discrimination procedure is the most frequently used in vivo model of hallucinogen activity. Historically, most drug discrimination studies have been conducted in the...
 
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Submitted by Jatelka Find all entries from this user
27-12-2007
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  DEA Microgram Analysis Manual - LSD Blotter Pictures 1987 Left click: open entry/Right click: save entry
The LSD Blotter Index, Dr. Edward Sykes Franzosa, Charles W. Harper, James H. Crockett. From DEA's Microgram Vol.XX, No.7, July 1987.

Scanned By Erowid, 2002-2003
 
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Submitted by pyroarchy Find all entries from this user
15-07-2008
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  Depersonalization and the use of LSD: a psychodynamic study. Left click: open entry/Right click: save entry
Am J Psychoanal. 1972;32(1):45-52.
Waltzer H.
 
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Submitted by ThirdEyeFloond Find all entries from this user
08-08-2008
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  Distinct temporal phases in the behavioral pharmacology of LSD: dopamine D2 receptor-mediated effects in the rat and implications for psychosis (2005) Left click: open entry/Right click: save entry
Psychopharmacology (Berl). 2005 Jul;180(3):427-35.

Marona-Lewicka D, Thisted RA, Nichols DE.
.
RATIONALE: The effect of LSD in humans has been described as occurring in two temporal phases. The behavioral effects in rats also occur in two temporal phases: an initial suppression of...
 
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01-06-2006
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Keywords: receptors pharmacology lsd dopamine
  EEG Coherence In Post-LSD Visual Hallucinations (2001) Left click: open entry/Right click: save entry
Psychiatry Res. 2001 Oct 1;107(3):151-63.

Abraham HD, Duffy FH.

LSD use in certain individuals may result in chronic visual hallucinations, a DSM-IV syndrome known as hallucinogen persisting perception disorder (HPPD). We studied 38 HPPD subjects with a mean of 9.7 years of persistent...
 
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16-01-2007
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  Effects of a hallucinogenic agent in totally blind subjects Left click: open entry/Right click: save entry 4 *
KRILL AE, ALPERT HJ, OSTFELD AM.


Arch Ophthalmol. 1963 Feb;69:180-5.
Effects of a hallucinogenic agent in totally blind subjects.

Study of the subjective effects of LSD in congenitally and non congenitally blind subjects. Describes the phenomenon of "visuals" seen by some of the subjects...
 
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Submitted by nnizzle Find all entries from this user
20-11-2009
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  Flashback to the 1960's: LSD in the Treatment of Autism (2007) Left click: open entry/Right click: save entry
Developmental Neurorehabilitation Jan-March 2007; 10 (1): 75-81

Sigafoos J, Green VA, Edrisinha C, Lancioni GE.

Between 1959 and 1974, several groups of researchers issued reports on the use of d-Lysergic Acid Diethylamide (LSD) in the treatment of children with autism. This paper reviews...

See also Drug History Documents 
 
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Submitted by Jatelka Find all entries from this user
09-10-2007
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Keywords: lsd therapy history
  Flashbacks in Theory and Practice (1998) Left click: open entry/Right click: save entry
The Heffter Review of Psychedelic Research Vol 1

Myer, Watkins and Carter

Really Interesting (and not too medical) review of HPDD. Also touches on cultural context in terms of visual perception changes.
 
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Submitted by Jatelka Find all entries from this user
28-03-2006
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  Further evidence that the delayed temporal dopaminergic effects of LSD are mediated by a mechanism different than the first temporal phase of action (D Marona-Lewicka & DE Nichols 2007) Left click: open entry/Right click: save entry
Pharmacology, Biochemistry and Behavior 87 (2007) 453–461

Authors: Danuta Marona-Lewicka and David E. Nichols
 
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23-01-2008
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  Gaddum and LSD: the birth and growth of experimental and clinical neuropharmacology research on 5-HT in the UK. Left click: open entry/Right click: save entry
Br J Pharmacol. 2008 Aug;154(8):1583-99. Epub 2008 May 26.

Green AR.

The vasoconstrictor substance named serotonin was identified as 5-hydroxytryptamine (5-HT) by Maurice Rapport in 1949. In 1951, Rapport gave Gaddum samples of 5-HT substance allowing him to develop a bioassay to both...

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Submitted by ThirdEyeFloond Find all entries from this user
07-09-2008
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  Halperngate (2006) Left click: open entry/Right click: save entry
MAPS Vernal Equinox 2006

Looks at John Halpern in relation to the Leonard Pickard Case

See also Drug History Documents 
 
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Submitted by Jatelka Find all entries from this user
12-03-2009
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  Handbook For The Therapeutic Use Of Lsd-25 Left click: open entry/Right click: save entry
HANDBOOK
FOR
THE THERAPEUTIC USE OF
LYSERGIC ACID DIETHYLAMIDE-25
INDIVIDUAL AND GROUP PROCEDURES
 
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Submitted by Toltec Find all entries from this user
09-02-2006
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  Harmful aspects of the LSD experience. Left click: open entry/Right click: save entry
J Nerv Ment Dis. 1967 Dec;145(6):464-74.
Ditman KS, Tietz W, Prince BS, Forgy E, Moss T.
 
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Submitted by ThirdEyeFloond Find all entries from this user
08-08-2008
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  Hofmann's original Synthesis of LSD-25 (in German) Left click: open entry/Right click: save entry
From Helvetica Chemica Acta Vol. 37

If anyone can translate German or find the English copy, please post asap and comment on here with a link to it.
 
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Submitted by Desertfox Find all entries from this user
25-07-2009
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  Hospital admissions due to lysergic-acid diethylamide Left click: open entry/Right click: save entry
Baker AA. (1970). Hospital admissions due to lysergic-acid diethylamide. Lancet, 295(7649):714-5.  
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Submitted by Bajeda Find all entries from this user
30-06-2009
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  In-Vivo Binding of LSD to 5HT-2 Receptors in Mouse Brain (Hartig et al, 1985) Left click: open entry/Right click: save entry
Life Sci. 1985 Aug 19;37(7):657-64.

Hartig PR, Scheffel U, Frost JJ, Wagner HN Jr.

The binding of 125I-LSD (2-[125I]-lysergic acid diethylamide) was studied in various mouse brain regions following intravenous injection of the radioligand. The high specific activity of 125I-LSD enabled the...
 
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11-08-2007
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  Influence of Environmental Context on Tolerance to LSD-Induced Behaviour in Primates (1986) Left click: open entry/Right click: save entry
Biol Psychiatry. 1986 Mar;21(3):314-7

Schlemmer RF Jr, Nawara C, Heinze WJ, Davis JM, Advokat C.

Interesting little article, which looks at how environment affects the development of tolerance to LSD-induced behaviours
 
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Submitted by Jatelka Find all entries from this user
11-08-2007
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  LSD and DOB: interaction with 5-HT2A receptors to inhibit NMDA receptor-mediated transmission in the rat prefrontal cortex (VL Arvanov et al 1999) Left click: open entry/Right click: save entry
European Journal of Neuroscience, Vol. 11, pp. 3064±3072, 1999

Viktor L. Arvanov, Xiaofu Liang, Angelo Russo and Rex Y. Wang

Abstract
Both the phenethylamine hallucinogen (±)-1-2,5-dimethoxy-4-bromophenyl-2-aminopropane (DOB), a selective serotonin 5-HT2A,2C receptor agonist, and the...

See also Phenethylamines Documents 
 
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Submitted by ThirdEyeFloond Find all entries from this user
09-02-2008
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  LSD and Genetic Damage: Is LSD chromosome damaging, carcinogenic, mutagenic or teratogenic? (1972) Left click: open entry/Right click: save entry
Science 172 421-440

Dishotsky et al

Here's a quote: "The damage...was the result of concentrations of drug and durations of exposure which could not be achieved in humans with reasonable dosage"
 
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08-05-2006
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  LSD and Its Lysergamide Cousins (2001) Left click: open entry/Right click: save entry
The Heffter Review of Psychedelic Research Vol 2

David E. Nichols, Ph.D.
 
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Submitted by Toltec Find all entries from this user
09-02-2006
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  LSD and Religious Experience (Pahnke, 1967) Left click: open entry/Right click: save entry 5 *
Looks at the different types of LSD experience, but focuses on the mystical. Also briefly covers psychedelic churches and peyotism

Discussion Thread
 
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Submitted by Jatelka Find all entries from this user
20-06-2007
229.03 Kbytes Hits 90
Keywords: experience lsd
  LSD before Leary. Sidney Cohen's critique of 1950s psychedelic drug research Left click: open entry/Right click: save entry
Novak SJ.
Isis. 1997;88(1):87-110
 
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Submitted by Heretic.Ape. Find all entries from this user
30-08-2007
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  LSD for the Treatment of Cluster Headaches RISK REPORT Left click: open entry/Right click: save entry
LSD for the Treatment of Cluster Headaches
RISK REPORT


By Jacqueline Sutton & Nathan Hebert
November 29, 2007

The cluster headache, described by one female sufferer as “more painful than childbirth”1 is a
neurological disorder that causes excruciating headache pain, usually behind one...
 
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Submitted by Guigz Find all entries from this user
28-10-2009
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