The co-administration of D-lysergic acid diethylamide (LSD; 'Acid') and 3,4-methylenedioxymethamphetamine (MDMA; 'Ecstasy'; 'XTC'), has reached a prevalence that has allowed for the street terminology 'candyflipping' to describe the...
d-Lysergic acid diethylamide (LSD), an indoleamine hallucinogen, produces profound alterations in mood, thought, and perception in humans. The brain site(s) that mediates the effects of LSD is...
Abraham HD.
“A chronic impairment of colour vision in users of LSD”.
Br J Psychiatry. 1982;140:518-20.
Submitted by trptamene
08-09-2007
625.41 Kbytes
Hits 50
Keywords: visionlsd
On November 3, National Geographic aired the first of several broadcasts of EXPLORER: Inside LSD. The producers did a good job of showing scientific research being done with LSD in different settings (past and current). The show included several segments about personal use. These ranged from...
Submitted by Anonymous
14-11-2009
215.22 Kbytes
Hits 16
Neuropsychopharmacology. 2002 May;26(5):634-42.
Nichols CD, Sanders-Bush E
Hallucinogenic drugs such as lysergic acid diethylamide (LSD) have profound effects on humans including hallucinations and detachment from reality. These remarkable behavioral effects have many similarities to the...
Submitted by Alfa
01-06-2006
354.23 Kbytes
Hits 148
Br J Psychiatry. 1971 Feb;118(543):229-30.
Malleson N.
Submitted by ThirdEyeFloond
08-08-2008
293.86 Kbytes
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Behav Brain Res. 1996;73(1-2):229-33.
Bonson KR, Murphy DL.
This study sought to investigate possible interactions between antidepressant agents and lysergic acid diethylamide (LSD) in humans through the use of retrospective questionnaires. Ten subjects were identified who used LSD during...
Tolerance is defined as a decrease in responsiveness to a drug after repeated administration. Tolerance to the behavioral effects of hallucinogens occurs in humans and animals. In this study,...
An early article on LSD titled, "Can This Drug Enlarge Man's Mind?" From the first volume of Psychedelic Review (Vol. I, No. 1, June 1963).
Author: Gerald Heard
Discussion Thread
Submitted by Expat98
31-05-2008
575.95 Kbytes
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Neuropsychopharmacology. 1996 Jun;14(6):425-36
Bonson KR, Buckholtz JW, Murphy DL.
This study investigates the possible interactions of antidepressant agents and hallucinogens in humans through structured interviews using a standardized questionnaire. Volunteer subjects recruited through...
Eight patients were seen within 15 minutes of intranasal self-administration of large amounts of pure D-lysergic acid diethylamide (LSD) tartrate powder. Emesis and collapse occurred along with signs of sympathetic...
Summary
1. Reactions induced by LSD, mescaline, psilocin, and psilocybin are qualitatively similar.
2. The time course of the psilocin and psilocybin reactions are shorter than those of LSD or mescaline reactions. li
4. Psilocin is approximately 1.4 times...
Submitted by enquirewithin
11-12-2009
743.36 Kbytes
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Benneyworth MA, Smith RL, Barrett RJ, Sanders-Bush E.
RATIONALE: The drug discrimination procedure is the most frequently used in vivo model of hallucinogen activity. Historically, most drug discrimination studies have been conducted in the...
Marona-Lewicka D, Thisted RA, Nichols DE.
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RATIONALE: The effect of LSD in humans has been described as occurring in two temporal phases. The behavioral effects in rats also occur in two temporal phases: an initial suppression of...
LSD use in certain individuals may result in chronic visual hallucinations, a DSM-IV syndrome known as hallucinogen persisting perception disorder (HPPD). We studied 38 HPPD subjects with a mean of 9.7 years of persistent...
Arch Ophthalmol. 1963 Feb;69:180-5.
Effects of a hallucinogenic agent in totally blind subjects.
Study of the subjective effects of LSD in congenitally and non congenitally blind subjects. Describes the phenomenon of "visuals" seen by some of the subjects...
Submitted by nnizzle
20-11-2009
526.69 Kbytes
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Between 1959 and 1974, several groups of researchers issued reports on the use of d-Lysergic Acid Diethylamide (LSD) in the treatment of children with autism. This paper reviews...
Br J Pharmacol. 2008 Aug;154(8):1583-99. Epub 2008 May 26.
Green AR.
The vasoconstrictor substance named serotonin was identified as 5-hydroxytryptamine (5-HT) by Maurice Rapport in 1949. In 1951, Rapport gave Gaddum samples of 5-HT substance allowing him to develop a bioassay to both...
Submitted by Jatelka
12-03-2009
157.99 Kbytes
Hits 60
HANDBOOK
FOR
THE THERAPEUTIC USE OF
LYSERGIC ACID DIETHYLAMIDE-25
INDIVIDUAL AND GROUP PROCEDURES
Submitted by Toltec
09-02-2006
358.76 Kbytes
Hits 174
J Nerv Ment Dis. 1967 Dec;145(6):464-74.
Ditman KS, Tietz W, Prince BS, Forgy E, Moss T.
Submitted by ThirdEyeFloond
08-08-2008
948.03 Kbytes
Hits 17
From Helvetica Chemica Acta Vol. 37
If anyone can translate German or find the English copy, please post asap and comment on here with a link to it.
Submitted by Desertfox
25-07-2009
1.22 Mbytes
Hits 21
Baker AA. (1970). Hospital admissions due to lysergic-acid diethylamide. Lancet, 295(7649):714-5.
Submitted by Bajeda
30-06-2009
303.67 Kbytes
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Keywords: lsd
Life Sci. 1985 Aug 19;37(7):657-64.
Hartig PR, Scheffel U, Frost JJ, Wagner HN Jr.
The binding of 125I-LSD (2-[125I]-lysergic acid diethylamide) was studied in various mouse brain regions following intravenous injection of the radioligand. The high specific activity of 125I-LSD enabled the...
Schlemmer RF Jr, Nawara C, Heinze WJ, Davis JM, Advokat C.
Interesting little article, which looks at how environment affects the development of tolerance to LSD-induced behaviours
Submitted by Jatelka
11-08-2007
266.90 Kbytes
Hits 54
Keywords: tolerancelsd
European Journal of Neuroscience, Vol. 11, pp. 3064±3072, 1999
Viktor L. Arvanov, Xiaofu Liang, Angelo Russo and Rex Y. Wang
Abstract
Both the phenethylamine hallucinogen (±)-1-2,5-dimethoxy-4-bromophenyl-2-aminopropane (DOB), a selective serotonin 5-HT2A,2C receptor agonist, and the...
Submitted by ThirdEyeFloond
09-02-2008
431.36 Kbytes
Hits 55
Science 172 421-440
Dishotsky et al
Here's a quote: "The damage...was the result of concentrations of drug and durations of exposure which could not be achieved in humans with reasonable dosage"
Submitted by Jatelka
08-05-2006
1.52 Mbytes
Hits 106
Keywords: lsd
The Heffter Review of Psychedelic Research Vol 2
David E. Nichols, Ph.D.
Submitted by Toltec
09-02-2006
263.06 Kbytes
Hits 151
Looks at the different types of LSD experience, but focuses on the mystical. Also briefly covers psychedelic churches and peyotism
LSD for the Treatment of Cluster Headaches
RISK REPORT
By Jacqueline Sutton & Nathan Hebert
November 29, 2007
The cluster headache, described by one female sufferer as “more painful than childbirth”1 is a
neurological disorder that causes excruciating headache pain, usually behind one...
Submitted by Guigz
28-10-2009
130.94 Kbytes
Hits 8