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Amphetamine Documents

Documents about Amphetamine, Adderall, Concerta & Ritalin, Methamphetamine

New entries announced in forum CHEMICAL & (SEMI-) SYNTHETIC DRUGS

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Adderall Documents [14 entries]

Concerta & Ritalin Documents [22 entries]

Methamphetamine Documents [58 entries]

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Entries

A behavioural economic analysis of alcohol, amphetamine, cocaine and ecstasy purchases by polysubstance misusers. (2004)

Left click: open entry/Right click: save entry

Drug Alcohol Depend. 2004 Oct 5;76(1):93-9

Harry R. Sumnall, Elizabeth Tyler, Graham F. Wagstaff, Jon C. Cole

Behavioural economic models of substance choice describe the relationship between changes in unit price and consumption. As the majority of UK non-dependent substance misusers are...

See also Ecstasy (MDMA, MDEA, MDA) Documents Cocaine & Crack Documents Alcohol Documents Drug Use Documents

Submitted by ThirdEyeFloond

16-01-2008
103.98 Kbytes Hits 303
Keywords: alcohol amphetamine mdma poly-drug polysubstance

A comparison of drug-seeking behavior maintained by d-amphetamine, l-deprenyl (selegiline) and d-deprenyl under a second-order schedule in squirrel monkeys (2006)

Psychopharmacology 2006 January; 183(4): 413–421

Sevil Yasar, József Gaál, Leigh V. Panlilio, Zuzana Justinova, Szecsö V. Molnár, Godfrey H. Redhi, and Charles W. Schindler

Rationale: l-Deprenyl (selegiline) is used in the treatment of Parkinson disease and has been proposed as an aid for...

Submitted by Jatelka

13-06-2008
217.34 Kbytes Hits 40

Acute d-Amphetamine Pretreatment Does Not Alter Stimulant Self-Administration in Humans (2007)

Pharmacology Biochemistry and Behaviour 2007 May; 87(1): 20–29

William W. Stoops, Andrea R. Vansickel, Joshua A. Lile, and Craig R. Rush

Recent clinical research indicates that d-amphetamine is effective in treating cocaine and methamphetamine dependence. There is concern, however, with the...

Submitted by Jatelka

12-06-2008
230.64 Kbytes Hits 36

Amphetamine effects in man: Paradoxical drowsiness and lowered electrical brain activity (CNV)

Joseph J. Tecce and Jonathan O. Cole

Thirteen of 20 normal adults given 10 milligrams of dextroamphetamine exhibited paradoxical drowsiness accompanied by lowered electrical brain activity (contingent negative variation, or CNV) in the first hour post-drug. During this period, seven subjects...

Submitted by Gradient

27-10-2009
1.95 Mbytes Hits 7

Amphetamine neurotoxicity: accomplishments and remaining challenges.

Neurosci Biobehav Rev. 2004 Jan;27(8):821-6.

McCann UD, Ricaurte GA.

In addition to the social, cultural and indirect medical complications of amphetamine analog abuse, this class of drugs is also known to have the potential to damage brain monoaminergic cells directly. Using methamphetamine...

Submitted by ThirdEyeFloond

27-05-2009
112.39 Kbytes Hits 25
Keywords: methamphetamine neurotoxicity

Amphetamine Use and Co-Occurring Psychological Problems: A Review of the Literature and Implications for Treament (2005)

Australian Psychologist, June 2005; 40(2): 87 – 94

A. Baker and S. Dawe

Looks at psychological symptoms in amphetamine users

Submitted by Jatelka

15-09-2007
111.18 Kbytes Hits 200
Keywords: treatment amphetamine

Amphetamine-induced dopamine release in human ventral striatum correlates with euphoria (2001)

Biological Psychiatry 2001 Jan 15;49(2):81-96

Drevets WC, Gautier C, Price JC, Kupfer DJ, Kinahan PE, Grace AA, Price JL, Mathis CA

BACKGROUND: Studies in experimental animals have implicated the mesolimbic dopaminergic projections into the ventral striatum in the neural processes...

Submitted by Jatelka

09-07-2009
228.34 Kbytes Hits 13

An evaluation of the cytochrome p450 inhibition potential of lisdexamfetamine in human liver microsomes. (2007)

Drug Metabolism and Disposition 2007 Jan;35(1):180-4

Krishnan S, Moncrief S.

The human cytochrome P450 (P450) system is implicated in many drug interactions. Lisdexamfetamine dimesylate (NRP104), the proposed generic name for a new agent under investigation for treatment of attention...

Submitted by staples

29-01-2008
73.63 Kbytes Hits 64
Keywords: lisdexamfetamine amphetamine cytochrome

Cellular and molecular mechanisms involved in the neurotoxicity of opioid and psychostimulant drugs

Abstract: Substance abuse and addiction are the most costly of all the neuropsychiatric disorders. In the last decades, much progress has been achieved in understanding the effects of the drugs of abuse in the brain. However, efficient treatments that prevent relapse have not been developed. Drug...

See also Opium, Opiate & Opioids Documents Pharmacology Documents Cocaine & Crack Documents

Submitted by Gradient

19-07-2009
569.08 Kbytes Hits 34

Comparative and interactive human psychopharmacologic effects of ketamine and amphetamine: implications for glutamatergic and dopaminergic model psychoses and cognitive function (2005)

Archives of General Psychiatry 2005 Sep;62(9):985-94

Krystal JH, Perry EB Jr, Gueorguieva R, Belger A, Madonick SH, Abi-Dargham A, Cooper TB, Macdougall L, Abi-Saab W, D'Souza DC.

BACKGROUND: In healthy individuals, ketamine hydrochloride and amphetamine sulfate produce cognitive,...

See also Ketamine Documents

Submitted by Jatelka

19-06-2008
217.18 Kbytes Hits 55

Comparisons between bupropion and dexamphetamine in a range of in vivo tests exploring dopaminergic transmission (2007)

British Journal of Pharmacology 2007 March; 150(6): 711–719

P Bredeloux, I Dubuc, and J Costentin

Background and purpose:: In the present study we investigated, in a range of in vivo tests whether the antidepressant bupropion, and its metabolites shared the dopamine releasing effect of the...

Submitted by Jatelka

13-06-2008
139.53 Kbytes Hits 41

Differential effects of amphetamine isomers on dopamine release

There is a lack of information regarding the effects of different amphetamine isomers on the body. After searching for a while, I found this article that provides a lot of great info on the topic.

Submitted by dark12

09-12-2008
399.72 Kbytes Hits 64

Do stimulants protect against psychiatric disorders in youth with ADHD? A 10-year follow-up study.

OBJECTIVE: Little is known about the effect of stimulant treatment in youth with attention-deficit/hyperactivity disorder (ADHD) on the subsequent development of comorbid psychiatric disorders. We tested the association between stimulant treatment and the subsequent development of psychiatric...

See also Stimulants in general Documents

Submitted by staples

07-08-2009
266.84 Kbytes Hits 9
Keywords: stimulants adhd

Dual intoxication with diazepam and amphetamine: this drug interaction probably potentiates myocardial ischemia (2007)

Med Hypotheses. Volume: 69, Issue: 2, Date: 2007 8 , Pages: 377-80

Starcevic, Boris. Sicaja, Mario

Drug-induced myocardial infarction is not a common phenomenon and the underlying mechanism has been related with the coronary artery spasm in the majority of cases. It is mainly related to...

See also Benzodiazepines Documents

Submitted by ThirdEyeFloond

14-01-2008
93.36 Kbytes Hits 192
Keywords: amphetamine diazepam

Early pharmacokinetics and clinical effects of oral d-amphetamine in normal subjects (1987)

Biological Psychiatry. Volume 22, Issue 11, 1987, Pages 1357-1368

Burt Angrist, June Corwin, Barbara Bartlik & Thomas Cooper

Seven normal subjects received 0.25 mg/kg D-amphetamine orally, both after an overnight fast and again after a standard breakfast. Plasma levels, subjective and...

Submitted by Bajeda

06-03-2008
961.60 Kbytes Hits 41
Keywords: pharmacokinetics dexamphetamine

Evaluation of Estradiol Administration on the Discriminative-Stimulus and Subject-Rated Effects of d-Amphetamine in Healthy, Pre-Menopausal Women (2007)

Pharmacology, Biochemistry and Behaviour 2007 Jun-Jul;87(2):258-66

Lile JA, Kendall SL, Babalonis S, Martin CA, Kelly TH.

Accumulating evidence suggests that estradiol might be responsible for the enhanced response to psychostimulants sometimes observed in females. In this study, 10 healthy...

Submitted by Jatelka

31-12-2007
326.63 Kbytes Hits 27
Keywords: pharmacology amphetamine

Following Several Days of Continuous Administration d-Amphetamine Acquires Hallucinogenic Properties (1980)

Psychopharmacology 68, 197 - 200 (1980)

Erik B. Nielsen, Tong H. Lee, and Gaylord Ellison

Submitted by Jatelka

18-05-2007
391.06 Kbytes Hits 160
Keywords: amphetamine hallucinogenic

Incomplete Submission for Amphetamine Wiki Article (Work in Progress)

This document is a portion of the information that SWIM has written about amphetamine. SWIM hopes that the complete document will eventually be of a high enough quality that it can be submitted as the Wiki article for amphetamine.

Many of the sections that are incomplete in this document have...

Submitted by DecoyPencil

10-09-2009
78.00 Kbytes Hits 29

Individual Differences in Drug Abuse Vulnerability: d-Amphetamine and Sensation-Seeking Status (2006)

Psychopharmacology 2006 Nov;189(1):17-25

Kelly TH, Robbins G, Martin CA, Fillmore MT, Lane SD, Harrington NG, Rush CR.

RATIONALE: While the personality dimensions of novelty seeking and sensation seeking are associated with drug abuse vulnerability, the mechanisms associated with this...

Submitted by Jatelka

31-12-2007
181.76 Kbytes Hits 53
Keywords: amphetamine

Individual Differences in Mood Reactions to d-Amphetamine: Test of Three Personality Factors (2000)

Journal of Psychopharmacology 2000;14(4):371-7

Corr PJ, Kumari V.

Individual differences in self-reported mood following either 5 mg or 10 mg d-amphetamine challenge were examined in order to test the modifying role of three factors of personality, viz., the Eysencks' psychoticism,...

Submitted by Jatelka

19-12-2007
111.49 Kbytes Hits 76
Keywords: amphetamine

Interactions Between Ethanol and Cocaine, Amphetamine, or MDMA in the Rat: Thermoregulatory and Locomotor Effects (2007)

Originally published in Psychopharmacology 2007, Published online Nov 27

Hamida SB, Plute E, Cosquer B, Kelche C, Jones BC, Cassel JC

RATIONALE: (+/-)-3,4-methylenedioxymethamphetamine (MDMA, ecstasy) is often taken recreationally with ethanol (EtOH). In rats, EtOH may potentiate...

See also Ecstasy (MDMA, MDEA, MDA) Documents Cocaine & Crack Documents

Submitted by Jatelka

22-01-2008
406.77 Kbytes Hits 49
Keywords: mdma ethanol cocaine amphetamine alcohol

Interactions of Amphetamine Analogues with Human Liver CYP2D6 (1997)

Biochemical Pharmacology Vol 53, 1605 - 1612, 1997

Wu, Otton, Inaba, Kallow and Sellers

More on the interaction of Amphetamine analogues with the cytochrome system

Submitted by Jatelka

18-05-2007
630.90 Kbytes Hits 35
Keywords: metabolism cytochrome amphetamine

Lisdexamfetamine dimesylate (Drug Discov. 2007 May;6(5):343-4)

Lisdexamfetamine dimesylate (Vyvanse; New River Pharmaceuticals/Shire), a prodrug of D-amphetamine, was approved by the US FDA in February 2007 for the treatment of attention-deficit/hyperactivity disorder.

Submitted by staples

29-01-2008
166.61 Kbytes Hits 74
Keywords: amphetamine lisdexamfetamine pharmacology

Locomotor Effects of Acute and Repeated Threshold Doses of Amphetamine and Methylphenidate: Relative Roles of Dopamine and Norepinephrine (2001)

Journal of Pharmacology and Experimental Therapeutics 2001 Mar;296(3):876-83

Kuczenski R, Segal DS.

The prescribed use of methylphenidate (Ritalin) in the treatment of attention deficit hyperactivity disorder has risen dramatically in recent years. The relative roles of dopamine,...

See also Concerta & Ritalin Documents

Submitted by Jatelka

31-12-2007
184.09 Kbytes Hits 63
Keywords: epinephrine pharmacology methylphenidate dopamine amphetamine

Medications and their effects on sleep (2004)

Qureshi A, Lee-Chiong T. Medical Clinics of North America. 2004;88(3):751–766.

Abstract
Although considered a passive process in the past, it is now known that falling asleep and passing through its various stages is an active process that is governed by certain groups of neurons in the brain....

See also Tobacco Documents Stimulants in general Documents Melatonin Documents Caffeine Documents Antidepressants Documents Anti-psychotics Documents Opium, Opiate & Opioids Documents Alcohol Documents Pharmacology Documents The Euphoric body Documents Z-Drugs Documents Benzodiazepines Documents Downers Documents

Submitted by staples

02-09-2009
240.68 Kbytes Hits 36
Keywords: clemastine amoxapine ssri insomnia chlorpheniramine maprotiline sertraline hydrate propoxyphene nefazodone risperidone histamine corticosteriod viagabatrin fluvoxamine reserpine haloperidol phenylpropanolamine tiagabine brofaromine rem gabapentin clofibrate lamotrigine tranylcypromine pseudoephedrine gaba gemfibrozil primidone phenelzine phenobarbital flurazepam spironolactone valproic antihistamine pentobarbital fluoxetine mexiletine phenytoin clomipramine paroxetine diphenhydramine moxonidine carbamazepine doxepin oxycodone diazepam imidazoline anticonvulsants desipramine oxazepam codeine terazosin anticholinergic imipramine opiate clonidine prazosin benztropine nortriptyline nicotine citalopram methyldopa levodopa amitriptyline neuroleptic chloral beta-blockers pramipexole zolpidem morphine caffeine hypolipidemic pergolide zaleplon moclobemide benzodiazepine antiarrhythmic bromocriptine venlafaxine mirtazapine barbiturate antihypertensive antiparkinsonian tricyclic midazolam antipsychotic cetirizine nonbenzodiazepine triazolam methadone antidepressants fexofenadine quetiapine trazodone melatonin amphetamine loratadine sertindole topiramate maoi alprazolam terfenadine chlorpromazine temazepam lorazepam alcohol hydroxyzine thioridazine stimulants lithium acid

Mood-Elevating Effects of d-Amphetamine and Incentive Salience: The Effect of Acute Dopamine Precursor Depletion (2007)

Journal of Psychiatry and Neurosciences 2007 Mar;32(2):129-36

Leyton M, aan het Rot M, Booij L, Baker GB, Young SN, Benkelfat C.

OBJECTIVE: Midbrain dopamine transmission is thought to regulate responses to rewarding drugs and drug-paired stimuli; however, the exact contribution,...

Submitted by Jatelka

15-09-2007
199.89 Kbytes Hits 61
Keywords: amphetamine dopamine

Neurochemical and Behavioural Differences Between d-Amphetamine and Methamphetamine in Rats (2003)

Psychopharmacology 2003 Feb;165(4):359-69

Shoblock JR, Sullivan EB, Maisonneuve IM, Glick SD.

RATIONALE: Methamphetamine (METH) and amphetamine (AMPH) are both abused psychostimulants. Although METH is generally accepted to be more addictive and potent than its analogue AMPH, there are no...

See also Methamphetamine Documents

Submitted by Jatelka

31-12-2007
360.85 Kbytes Hits 68
Keywords: pharmacology methamphetamine glutamate dopamine amphetamine

NEUROTOXIC ACTION OF HALOGENATED AMPHETAMINES

No abstract

Submitted by helikophis

07-06-2009
3.06 Mbytes Hits 10
Keywords: 4-fluoro-amphetamine

Performance and alertness effects of caffeine, dextroamphetamine, and modafinil during sleep deprivation (2005)

J Sleep Res. 2005 Sep;14(3):255-66.

Wesensten NJ, Killgore WD, Balkin TJ

At the doses tested, caffeine, dextroamphetamine, and modafinil are equally effective for approximately 2–4 h in restoring simple psychomotor performance and objective alertness. The duration of these benefits vary in...

See also Modafinil Documents Stimulants in general Documents

Submitted by Bajeda

01-05-2007
208.25 Kbytes Hits 139
Keywords: modafinil caffeine amphetamine stimulants

Personality and the Subjective Effects of Acute Amphetamine in Healthy Volunteers (2006)

Neuropsychopharmacology 2006 May;31(5):1064-74

White TL, Lott DC, de Wit H.

Individual differences in the positive mood and other subjective effects of d-amphetamine have been linked to personality traits related to sensation seeking. The current study extends these associations to separate...

Submitted by Jatelka

15-08-2006
146.63 Kbytes Hits 104
Keywords: amphetamine

Physical and mental health problems in amphetamine users from metropolitan Adelaide, Australia (1998)

Drug and Alcohol Review. Abingdon: Jun 1998. Vol. 17, Iss. 2; pg. 187-196.

Niki Vincent, Jodie Shoobridge, Alex Ask, Steve Allsop, Robert Ali.

Phase I of this study was designed to inform the development of a range of responses to hazardous and harmful amphetamine use. Research techniques...

See also Amphetamine and Methamphetamine Addiction Documents By Country/Region Documents

Submitted by Bajeda

06-03-2008
906.57 Kbytes Hits 70
Keywords: physical-health mental-health amphetamine dependence

Potential Adverse Effects of Amphetamine Treatment on Brain and Behavior: A Review (2009)

Molecular Psychiatry, 14(2): 123–142 (February 2009)

Steven M. Berman (1), Ronald Kuczenski (2), James T. McCracken (1), and Edythe D. London (1)

(1) Departments of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California Los Angeles, CA
(2)...

Submitted by Phenoxide

07-01-2010
124.79 Kbytes Hits 0
Keywords: methamphetamine amphetamine adhd adderall neurotoxicity

Psychostimulant-like effects of p-fluoroamphetamine in the rat

The present study was undertaken to compare the pharmacological properties of p-fluoroamphetamine with those of amphetamine and of other halogenated amphetamines, using several in vivo and in vitro tests. These included substitution testing in (+)-amphetamine (1 mg/kg, 5.4 μmol/kg, i.p.)-,...

Submitted by helikophis

07-06-2009
834.67 Kbytes Hits 9
Keywords: 4-fluoro-amphetamine

Qualitative review of serotonin syndrome, ecstasy (MDMA) and the use of other serotonergic substances: hierarchy of risk (2007)

Australian and New Zealand Journal of Psychiatry 2007 Aug;41(8):649-55

Silins E, Copeland J, Dillon P.

Growth of the antidepressant market and widespread use of the illicit drug ecstasy (methylenedioxymethamphetamine; MDMA) creates a need to delineate the potential harms associated with the...

See also Ecstasy (MDMA, MDEA, MDA) Documents Cocaine & Crack Documents Drug Use Documents

Submitted by Jatelka

09-10-2007
62.97 Kbytes Hits 165
Keywords: serotonin-syndrome amphetamine maoi mdma cocaine

Selctive Involvement of the Cytochrome P450 2D Subfamily in In Vivo 4-Hydroxylation of Amphetamine in the Rat (2000)

Drug Metabolism and Disposition 2000 Mar;28(3):348-53

Law MY, Slawson MH, Moody DE.

The cytochrome P450 (P450) 2D subfamily catalyzes ring hydroxylation of amphetamines. We tested the hypothesis that P450 2D is selectively involved in amphetamine 4-hydroxylation. Urinary elimination of...

Submitted by Jatelka

18-05-2007
168.92 Kbytes Hits 72
Keywords: metabolism amphetamine cytochrome

Serotonin toxicity with therapeutic doses of dexamphetamine and venlafaxine

Medical Journal of Australia 2002 Mar 4;176(5):240-1.

Prior FH, Isbister GK, Dawson AH, Whyte IM

No abstract available

See also Antidepressants Documents

Submitted by staples

07-03-2008
105.41 Kbytes Hits 71
Keywords: serotonin-syndrome snri dexamphetamine

Sex Differences in (+)-Amphetamine- and (+)-Methamphetamine-induced Behavioral Response in Male and Female Sprague-Dawley Rats (2007)

Pharmacology Biochemistry and Behaviour 2007 January; 86(1): 140–149

Alessandra Milesi-Hallé, Donald E. McMillan, Elizabeth M. Laurenzana, Kelly A. Byrnes-Blake, and S. Michael Owens

(+)-Methamphetamine (METH) and (+)-amphetamine (AMP) are structurally similar drugs that are reported to...

See also Methamphetamine Documents

Submitted by Jatelka

12-06-2008
426.32 Kbytes Hits 48

Similar discriminative-stimulus effects of D-amphetamine in women and men (2007)

Pharmacology Biochemistry and Behaviour 2007 Jun-Jul;87(2):289-96.

Vansickel AR, Lile JA, Stoops WW, Rush CR.

The results of controlled non-human animal and human laboratory studies are mixed regarding whether women and men respond differently to stimulant drugs. In order to assess...

Submitted by Jatelka

18-05-2008
198.40 Kbytes Hits 29

The effect of amphetamines on selected physiological components related to athletic success.

Six male college students were tested under two experimental conditions; amphetamine and no amphetamine. Each subject was tested three times under each condition. A double-blind placebo-controlled approach was employed and on six consecutive Fridays the subjects received either a placebo or 15 mg...

Submitted by Gradient

24-06-2009
888.87 Kbytes Hits 7

The neurotoxicity of amphetamines: Bridging drugs of abuse and neurodegenerative disorders (2006)

Experimental Neurology 2006 Sep;201(1):24-31

Iacovelli L, Fulceri F, De Blasi A, Nicoletti F, Ruggieri S, Fornai F.

Amphetamine derivatives are the most commonly abused drugs. These compounds have been known for many years to induce neurotoxicity. However, recent findings have highlighted...

Submitted by Sitbcknchill

03-12-2006
347.68 Kbytes Hits 174
Keywords: neurotoxicity amphetamine

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