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View Full Version : Drug info - Alterations in brain 5-hydroxytryptamine metabolism during the 'withdrawal' phase after chronic treatment with diazepam and bromazepam (1977)


Jatelka
03-05-2008, 13:08
A new entry has been added to Drugs Archive

Description:
British Journal of Pharmacology 1977 May;60(1):3-9

Agarwal RA (http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Agarwal%20RA%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsP anel.Pubmed_DiscoveryPanel.Pubmed_RVAbstractPlus), Lapierre YD (http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Lapierre%20YD%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsP anel.Pubmed_DiscoveryPanel.Pubmed_RVAbstractPlus), Rastogi RB (http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Rastogi%20RB%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsP anel.Pubmed_DiscoveryPanel.Pubmed_RVAbstractPlus), Singhal RL (http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Singhal%20RL%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsP anel.Pubmed_DiscoveryPanel.Pubmed_RVAbstractPlus)

Looks at the effects of benzodiazepine withdrawal on serotonin

To check it out, rate it or add comments, visit Alterations in brain 5-hydroxytryptamine metabolism during the 'withdrawal' phase after chronic treatment with diazepam and bromazepam (1977) (http://www.drugs-forum.com/forum/local_links.php?linkid=4983&catid=129)
The comments you make there will appear in the posts below.

oggy
03-05-2008, 18:53
Looks like diazepam is much worse than bromazepam for lowering tryptophan
hydroxylase activity and tryptophan levels. Still looking into the MAO side of things. Found some info on MAO http://en.wikipedia.org/wiki/MAO