View Full Version : Combinations - Benzodiazepines and Oxycodone
SWIMS girl took 10 mg of clonazepam while drinking alcohol yesterday. Very foolish. Today she swallowed 10 mg of oxycontin as well. Exactly how dangerous would this be, not counting the alcohol, cuz that one SWIM knows is dumb to mix with benzos, but the clonazepam/oxycontin mix? SWIM knows taking them together is dumb, but would there be less risk involved considering they were taken a day apart? SWIM has not heard from his girl since this morning and she should have been home a few hours ago. Maybe it is just paranoia. Just worried...
That is potentially a very dangerous mix. 10mg of clonazepam alone would be enough to knock many people out. Fingers crossed she is OK but SWIY should have a very serious chat with her about this.
jesusfreak666er
28-06-2006, 16:29
how much time elapsed... if it was yesterday and today, swim's girl should be fine... klonapin has a long half life but still, if 10 hours has elapsed... swiy's girl should be fine, not to mention 10mg of oxycontin (didnt know they made made 10mg) is a low dose, aslong as time seal isnt broke, swim has a feeling swiy means oxycodone not oxycontin. but swiy should chill, the alc and klonapin is out of her system.
With half life of 18 to 50 hours there would still be quite a bit of clonazepam in her system.
Thank you, yes SWIM will definitly have a serious talk with her. He loves his girl you know, so maybe he overreacts a bit but still, its no joke mixing those things SWIM has heard. Time between intakes were 12-14 hours.
Update: Everything OK, she promised to not do it again. SWIM showed her a couple of threads on this forum, and she realized why it was dangerous. Drugs-forum prevents future harm, wonderful!
Fantasian
28-06-2006, 19:01
F is glad, SWIM's girl is lucky to have him.
Vali-yum
29-06-2006, 09:33
Just so swim understands, it's not good to take Xanax, Oxycotin, and drink alcohol?
And if not why (swim likes this combo)?
Mixing drugs which can have additive effects is not recommended. All 3 are depressants.
Mixing depressants means: Increased sedation and increased risk of respiratory depression. Potential for becoming unconscious, being unable to protect ones airway, stopping breathing and/or choking on your own vomit.
Vali-yum
29-06-2006, 09:57
Mixing drugs which can have additive effects is not recommended. All 3 are depressants.
Mixing depressants means: Increased sedation and increased risk of respiratory depression. Potential for becoming unconscious, being unable to protect ones airway, stopping breathing and/or choking on your own vomit.
That's why swim likes adding Ritalin, which would be known as speed balling, if swim understands correctly...
And swim doesn't over do it, swim knows swims limits.
Excellent: So Not only does SWIY mix depressants they make the combo EVEN MORE dangerous by adding an upper.
This puts TREMENDOUS stress on the cardiovascular system.
*PEOPLE DIE FROM THIS KIND OF THING! DO NOT TRY THIS AT HOME KIDS*
Vali-yum
29-06-2006, 11:05
Excellent: So Not only does SWIY mix depressants they make the combo EVEN MORE dangerous by adding an upper.
This puts TREMENDOUS stress on the cardiovascular system.
*PEOPLE DIE FROM THIS KIND OF THING! DO NOT TRY THIS AT HOME KIDS*
Well basically swim likes to dink alot.. While swim drinks swim likes to toot ritalin. Sometimes swim mixes the ritalin with a little bit of cotin, but never bumps more than 10-15mg of it... Swim likes xanax too, but usually it's one or the other..
It's not like swim drinks a 12 pack, takes a blue xanny, toots a 20 mg ritalin, and then boofs a 40 mg oxycotin...
Swim told me it's more like 8-10 beers, 10-15 mg of ritalin, and 10 mg of cotin..
Vali-yum
29-06-2006, 11:06
Swim runs about 3 miles a day...:D
bewilderment
29-06-2006, 19:05
Personally, I wouldn't worry too much about mixing a small amount of benzos (note: small--think recommended dosage on the bottle, not 10mg of klonopin that's an incredibly large amount in and of itself). I also think taking a small amount of oxy with a little alcohol (not much, maybe a drink or two) is fine also. But, taking high doses of any of these drugs and then taking a moderate to high dose of any other drug (much less two other drugs which affect respiration and heart rate) is asking for trouble. And, even if there were no incredibly harmful effects, it would probably be unlikely that one could recall the events so if any fun was had then it would scarcely be remembered anyway.
SWIH, you were right to give your girlfriend a little chat. I certainly would.
Also, what sort of tolerance to klonopin did she have to begin with?
what sort of tolerance to klonopin did she have to begin with?
None. SWIM and her were on truly massive amounts of benzos a few months back, but she had not been touching the stuff for maybe 2 months this time. I dont know, 10 mg is considered a small dose around here, but on the other hand a lot of people here are not exactly bright either^^
:eek:
10 mg is considered a small dose around here
I shudder to think what is considered a high dose...
bewilderment
29-06-2006, 20:50
Swim found just 1mg of clonazepam to be a perfectly fine dose when she had no tolerance to them. In fact, 1mg was often enough to put her to sleep or mellow her out during a bad trip. Swim has only taken massive doses of benzos (i.e. 120mg of diazepam) when she was addicted to benzos and taking them daily over an extended period of time. Once swim administered around 5-6mg of clonazepam to her wife when she was having a lot of trouble with some 5-meo-amt (she was shaking pretty bad and her heart was racing and SWIM was worried for her health). She spent the entire next day stumbling around like she was a drunk and it she wasn't completely baseline until sometime the second day afterwards.
All, I can say is "wow". I hope none of your friends end up in the hospital with doses like that.
Also, if part of this was because she wanted to potentiate the oxy of something then perhaps she should just consider drinking grapejuice. Swim has no experience with this combo, but hears that it's not bad. Certainly a hell of a lot safer.
BUZZFACTOR
30-06-2006, 00:19
the triple threat of benzos,booze, and opiates kills people. Remove the alcohol
Ehh.. even without the alcohol. Benzos and opiates can cause death by respritary depression.
Fantasian
30-06-2006, 20:36
Ehh.. even without the alcohol. Benzos and opiates can cause death by respritary depression.
Definately, most drug combinations are dangerous and only for the very experienced and dose aware and even then they still are high risk activities.
upperdecker
21-06-2007, 03:53
SWIM snorted a little more than half of a 80mg of generic Oxycontin and isn't feeling GREAT!, just good. SWIM didn't sniff all this at once, but within a couple of hours. SWIM also takes 3mg of Clonazepam a day in the morning all at once. Would this have an effect on the high?
allyourbase
21-06-2007, 04:11
in SWIMs homble opinion benzodiazapines detract from the euphoria of opiates, though they add to the analgesic effect.
They will also increase sedation and the risk of respiratory depression. SWIJ gues amnesia will be more prominent also.
Daytona71
28-06-2007, 22:07
SWIM's pain clinic Dr. said on the last visit that they do inhibit the effctiveness of opioids but SWIM has not seen a paper describing that and would not believe that until he did. The clinic is trying to get patients off of Valium in particular and have already stopped prescribing SOMA which can be quite nasty anyways and dangerous to the uniniated. I'll try to research this claim.
According to this piece of research, opiates antagonise GABA responses:
http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=7066678&dopt=Abstract
That would achieve the opposite effect of benzodiazepines, which improve GABA responses.
I've read that benzodiazepines are sometimes prescribed to opiate addicts during withdrawal, there may be some relevence.
This is confused by the fact that I've also read opiates induce euphoria through GABA-mediated dopamine release in certain parts of the brain. Hmm.
yes it will. some benzo/opiate combos are not even addiciive, they are MULTIPLICATIVE.
SWIH's doctor told him that a high dose of lorazepam can potentiate the effects of alcohol by up to 10 times, depending on tolerance and general state of health.
benzos and opiates go well hand in hand and benzos make opiates even better. however, this is also a great way to kill yourself easily if you overdose, and with the multiplicative thing, that can go VERY fast. please be careful what you do, and never do this combo home alone, only if a friend is there.
if you're nodding away too much and your heartbeat goes down very much as well as your blood pressure, call the ambulance and tell them what you took. it'll save your life. and doctors are not allowed to report you to the police, at least here where SWIH lives. they're bond by their professional discretion.
carousel
01-08-2007, 18:46
if someone swim knows took .5 mg of k-pin in morning after taking 2.5 mg's the day before would it be safe to take 10-20 mg of hydrocodone later that day?
Please always include the chemical name of pharmaceutical drugs in your posts. This can be easily obtained from Google or other search engine. Doing so will avoid confusion on this international forum.
From the rules (http://www.drugs-forum.com/forum/announcement.php?f=35&a=1):
• Use descriptive Topic Subject. This will help others find what they want to read. Topics with bad Topic subjects may be deleted! - there's nothing more annoying than looking at all those stupid "A stupid question" subject lines. I mean, I'm damn lazy, but how hard is it to type "A stupid question about (insert something here)"? As a rule of thumb, most thread titles should include the full name of the drug discussed.
A rule many tend to forget will cause a mass of warnings soon... (http://www.drugs-forum.com/forum/showthread.php?t=23289)
Thank you
Thread title edited
SpaceCadetGlow
02-08-2007, 07:51
your friend will be fine, as long as he isn't allergic to either drugs. one of my friends takes .5-1mg clonazepam (klonopin) every day and uses hydrocodone frequently; his dose is usually about 30 mg (hydrocodone). Really the only potential downside to the combination would be excessive sedation.
Something that should always be stressed is that mixing downers can be extremely dangerous: Extreme caution is advised
Excessive sedation and amnesia are one end of the spectrum, depressed respiration and being unable to protect one's airway the other.
Please also bear in mind that tolerance to the drugs will also play a part, and a perfect dose for some flamingos could well kill another.
cheetahwhisker
06-08-2007, 03:01
Back when swim used to I.V. heroin he almost died because he took his usual dose of H but did'nt think the two bars he took earlier mattered. Swim woke up with paremedics standing over him, having just given him narcan to reverse the OD. If swim was alone and not with other people when he booted he would have died according to the paremedics. Swim say that benzos do intensify the effects of opiates but it depends on the desired effect that you are looking for. Everybody is different so everybody might not like the slow euphoric combination. Just be very carefull, and try not to do it alone.
carousel
17-08-2007, 03:59
Is it O.K. to take a 10 mg lortab if swim's friend takes 1.0 ativans every morning?